Citrus Polyphenol Hesperidin Stimulates Production of Nitric Oxide in Endothelial Cells while Improving Endothelial Function and Reducing Inflammatory Markers in Patients with Metabolic Syndrome

CONTEXT: Hesperidin, a citrus flavonoid, and its metabolite hesperetin may have vascular actions relevant to their health benefits. Molecular and physiological mechanisms of hesperetin actions are unknown. OBJECTIVE: We tested whether hesperetin stimulates production of nitric oxide (NO) from vascul...

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Main Authors: Rizza, Stefano, Muniyappa, Ranganath, Iantorno, Micaela, Kim, Jeong-a, Chen, Hui, Pullikotil, Philomena, Senese, Nicoletta, Tesauro, Manfredi, Lauro, Davide, Cardillo, Carmine, Quon, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2011
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Hot Topics in Translational Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085197/
https://ncbi.nlm.nih.gov/pubmed/21346065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-2879
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