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Treatment with the phosphodiesterase type 4 inhibitor rolipram fails to inhibit blood brain barrier disruption in MS
Rolipram, a prototypic phosphodiesterase-4 inhibitor is highly effective in suppressing Th1 autoimmunity in multiple animal models, including experimental autoimmune encephalomyelitis (EAE). Additionally, Rolipram has been extensively studied as a potential neuroprotective agent. Based on its anti-i...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085182/ https://ncbi.nlm.nih.gov/pubmed/19776093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458509345903 |
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