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Existence of rolipram-sensitive phosphodiesterase in rat megakaryocyte.

1. The effect of rolipram (ME3176) on ADP- and IP3-induced repetitive IK(Ca) in rat megakaryocyte was investigated by use of the nystatin perforated patch and conventional whole-cell patch-clamp techniques. 2. The ADP-induced IK(Ca) was depressed by treatment with rolipram in a concentration-depende...

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Autors principals: Akaike, N., Uneyama, H., Kawa, K., Yamashita, Y.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175734/
https://ncbi.nlm.nih.gov/pubmed/7691362
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