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Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide.
Recently several groups reported a dramatic improvement of reporter gene transfection efficiency using a fusogenic peptide, derived from the Influenza hemagglutinin envelop protein. This peptide changes conformation at acidic pH and destabilizes the endosomal membranes thus resulting in an increased...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1994
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC308518/ https://ncbi.nlm.nih.gov/pubmed/7984418 |
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