Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide.

Recently several groups reported a dramatic improvement of reporter gene transfection efficiency using a fusogenic peptide, derived from the Influenza hemagglutinin envelop protein. This peptide changes conformation at acidic pH and destabilizes the endosomal membranes thus resulting in an increased...

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Hlavní autoři: Bongartz, J P, Aubertin, A M, Milhaud, P G, Lebleu, B
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC308518/
https://ncbi.nlm.nih.gov/pubmed/7984418
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