Knockdown of NPM1 by RNA Interference Inhibits Cells Proliferation and Induces Apoptosis in Leukemic Cell Line

Nucleophosmin (NPM1) is an abundant and ubiquitously expressed phosphoprotein that is known to influence solid tumors progression. However, little is known about the role of NPM1 in leukemia. Here, we knocked down the NPM1 expression by RNA interference to investigate the role of NPM1 in leukemic ce...

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Autors principals: Qin, Feng-Xian, Shao, Hui-Yuan, Chen, Xian-Chun, Tan, Shi, Zhang, Hui-Juan, Miao, Zong-Yu, Wang, Li, Hui-Chen, Zhang, Ling
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2011
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085175/
https://ncbi.nlm.nih.gov/pubmed/21537492
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