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Knockdown of NPM1 by RNA Interference Inhibits Cells Proliferation and Induces Apoptosis in Leukemic Cell Line

Nucleophosmin (NPM1) is an abundant and ubiquitously expressed phosphoprotein that is known to influence solid tumors progression. However, little is known about the role of NPM1 in leukemia. Here, we knocked down the NPM1 expression by RNA interference to investigate the role of NPM1 in leukemic ce...

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Detalhes bibliográficos
Main Authors: Qin, Feng-Xian, Shao, Hui-Yuan, Chen, Xian-Chun, Tan, Shi, Zhang, Hui-Juan, Miao, Zong-Yu, Wang, Li, Hui-Chen, Zhang, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085175/
https://ncbi.nlm.nih.gov/pubmed/21537492
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