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Local Controlled Delivery of Anti-Neoplastic RNAse to the Brain
PURPOSE: Antineoplastic RNAse proteins, also known as Amphibinases, have been shown effective against various solid tumors but were found selectively neurotoxic to Purkinje cells in the cerebellum. This work describes the use of a waxy biodegradable poly(ricinoleic-co-sebacic acid) for the local con...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085080/ https://ncbi.nlm.nih.gov/pubmed/19415468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9893-3 |
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