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MOHITO, a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell context

The mouse pro-B cell line Ba/F3 has gained major interest as a model system to investigate oncogenic tyrosine kinases and to determine the efficacy of kinase inhibitors. While Ba/F3 cells are suitable to study oncogenic kinases derived from various cell types, the signaling networks in Ba/F3 cells a...

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Detalhes bibliográficos
Main Authors: Kleppe, Maria, Mentens, Nicole, Tousseyn, Thomas, Wlodarska, Iwona, Cools, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084928/
https://ncbi.nlm.nih.gov/pubmed/21193420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.035931
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