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Rac1 Deletion Causes Thymic Atrophy

The thymic stroma supports T lymphocyte development and consists of an epithelium maintained by thymic epithelial progenitors. The molecular pathways that govern epithelial homeostasis are poorly understood. Here we demonstrate that deletion of Rac1 in Keratin 5/Keratin 14 expressing embryonic and a...

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Détails bibliographiques
Auteurs principaux: Hunziker, Lukas, Aznar Benitah, Salvador, Braun, Kristin M., Jensen, Kim, McNulty, Katrina, Butler, Colin, Potton, Elspeth, Nye, Emma, Boyd, Richard, Laurent, Geoff, Glogauer, Michael, Wright, Nick A., Watt, Fiona M., Janes, Sam M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084817/
https://ncbi.nlm.nih.gov/pubmed/21559396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019292
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