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Rac1 Deletion Causes Thymic Atrophy

The thymic stroma supports T lymphocyte development and consists of an epithelium maintained by thymic epithelial progenitors. The molecular pathways that govern epithelial homeostasis are poorly understood. Here we demonstrate that deletion of Rac1 in Keratin 5/Keratin 14 expressing embryonic and a...

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Bibliografiska uppgifter
Huvudupphovsmän: Hunziker, Lukas, Aznar Benitah, Salvador, Braun, Kristin M., Jensen, Kim, McNulty, Katrina, Butler, Colin, Potton, Elspeth, Nye, Emma, Boyd, Richard, Laurent, Geoff, Glogauer, Michael, Wright, Nick A., Watt, Fiona M., Janes, Sam M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084817/
https://ncbi.nlm.nih.gov/pubmed/21559396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019292
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