Receptor Activator of NF-kB (RANK) Expression in Primary Tumors Associates with Bone Metastasis Occurrence in Breast Cancer Patients

BACKGROUND: Receptor activator of NFkB (RANK), its ligand (RANKL) and the decoy receptor of RANKL (osteoprotegerin, OPG) play a pivotal role in bone remodeling by regulating osteoclasts formation and activity. RANKL stimulates migration of RANK-expressing tumor cells in vitro, conversely inhibited b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Santini, Daniele, Schiavon, Gaia, Vincenzi, Bruno, Gaeta, Laura, Pantano, Francesco, Russo, Antonio, Ortega, Cinzia, Porta, Camillo, Galluzzo, Sara, Armento, Grazia, La Verde, Nicla, Caroti, Cinzia, Treilleux, Isabelle, Ruggiero, Alessandro, Perrone, Giuseppe, Addeo, Raffaele, Clezardin, Philippe, Muda, Andrea Onetti, Tonini, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084800/
https://ncbi.nlm.nih.gov/pubmed/21559440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019234
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados