Age- and Disease-Dependent HERV-W Envelope Allelic Variation in Brain: Association with Neuroimmune Gene Expression

BACKGROUND: The glycoprotein, Syncytin-1, is encoded by a human endogenous retrovirus (HERV)-W env gene and is capable of inducing neuroinflammation. The specific allele(s) responsible for Syncytin-1 expression in the brain is uncertain. Herein, HERV-W env diversity together with Syncytin-1 abundanc...

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Main Authors: Bhat, Rakesh K., Ellestad, Kristofor K., Wheatley, B. Matt, Warren, Rene, Holt, Robert A., Power, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084769/
https://ncbi.nlm.nih.gov/pubmed/21559469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019176
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