Apoptosis Inducing Effect of Plumbagin on Colonic Cancer Cells Depends on Expression of COX-2

Plumbagin, a quinonoid found in the plants of the Plumbaginaceae, possesses medicinal properties. In this study we investigated the anti-proliferative and apoptotic activity of plumbagin by using two human colonic cancer cell lines, HT29 and HCT15. IC50 of Plumbagin for HCT15 and HT29 cells (22.5 µM...

Full description

Saved in:
Bibliographic Details
Main Authors: Subramaniya, Bharathi Raja, Srinivasan, Gayathri, Mohammed Sadullah, Sakeena Sadullah, Davis, Nimitha, Baddi Reddi Subhadara, Lakshmi, Halagowder, Devaraj, Sivasitambaram, Niranjali Devaraj
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084694/
https://ncbi.nlm.nih.gov/pubmed/21559086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018695
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items