Apoptosis Inducing Effect of Plumbagin on Colonic Cancer Cells Depends on Expression of COX-2

Plumbagin, a quinonoid found in the plants of the Plumbaginaceae, possesses medicinal properties. In this study we investigated the anti-proliferative and apoptotic activity of plumbagin by using two human colonic cancer cell lines, HT29 and HCT15. IC50 of Plumbagin for HCT15 and HT29 cells (22.5 µM...

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Detalhes bibliográficos
Main Authors: Subramaniya, Bharathi Raja, Srinivasan, Gayathri, Mohammed Sadullah, Sakeena Sadullah, Davis, Nimitha, Baddi Reddi Subhadara, Lakshmi, Halagowder, Devaraj, Sivasitambaram, Niranjali Devaraj
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084694/
https://ncbi.nlm.nih.gov/pubmed/21559086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018695
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