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Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation

The canonical Wnt pathway plays an important role in the regulation of cell proliferation and differentiation. Activation of this signaling pathway causes disruption of the Axin/adenomatous polyposis coli/glycogen synthase kinase 3β complex, resulting in stabilization of β-catenin and its associatio...

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Detalhes bibliográficos
Main Authors: Zhang, Long, Zhou, Fangfang, van Laar, Theo, Zhang, Juan, van Dam, Hans, ten Dijke, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084683/
https://ncbi.nlm.nih.gov/pubmed/21411632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-12-0985
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