Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation

Yeast Hsp104 and its bacterial homolog, ClpB, are Clp/Hsp100 molecular chaperones and AAA+ ATPases. Hsp104 and ClpB collaborate with the Hsp70 and DnaK chaperone systems, respectively, to retrieve and reactivate stress-denatured proteins from aggregates. The action of Hsp104 and ClpB in promoting ce...

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Dettagli Bibliografici
Autori principali: Miot, Marika, Reidy, Michael, Doyle, Shannon M., Hoskins, Joel R., Johnston, Danielle M., Genest, Olivier, Vitery, Maria-Carmen, Masison, Daniel C., Wickner, Sue
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084080/
https://ncbi.nlm.nih.gov/pubmed/21474779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102828108
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