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Hsp70 and Hsp90 of E. coli directly interact for collaboration in protein remodeling

Hsp90 is a highly conserved molecular chaperone that remodels hundreds of client proteins, many involved in the progression of cancer and other diseases. It functions with the Hsp70 chaperone and numerous cochaperones. The bacterial Hsp90 functions with an Hsp70 chaperone, DnaK, but is independent o...

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Bibliografische gegevens
Gepubliceerd in:J Mol Biol
Hoofdauteurs: Genest, Olivier, Hoskins, Joel R., Kravats, Andrea N., Doyle, Shannon M., Wickner, Sue
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663108/
https://ncbi.nlm.nih.gov/pubmed/26482100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.10.010
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