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A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets

Proneural genes such as Ascl1 are known to promote cell cycle exit and neuronal differentiation when expressed in neural progenitor cells. The mechanisms by which proneural genes activate neurogenesis—and, in particular, the genes that they regulate—however, are mostly unknown. We performed a genome...

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Bibliographic Details
Main Authors: Castro, Diogo S., Martynoga, Ben, Parras, Carlos, Ramesh, Vidya, Pacary, Emilie, Johnston, Caroline, Drechsel, Daniela, Lebel-Potter, Mélanie, Garcia, Laura Galinanes, Hunt, Charles, Dolle, Dirk, Bithell, Angela, Ettwiller, Laurence, Buckley, Noel, Guillemot, François
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084027/
https://ncbi.nlm.nih.gov/pubmed/21536733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.627811
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