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Is tau a suitable therapeutical target in tauopathies?

Tau is an intracellular protein, found mainly in neurons, but it can also be found in the extracellular space in pathological situations. Here we discuss whether intracellular tau, in aggregated form or modified by phosphorylation, could be toxic inside a neuron. On the other hand, it has been propo...

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Bibliografiska uppgifter
Huvudupphovsmän: de Barreda, Elena Gomez, Avila, Jesús
Materialtyp: Artigo
Språk:Inglês
Publicerad: Baishideng Publishing Group Co., Limited 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083962/
https://ncbi.nlm.nih.gov/pubmed/21540993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v1.i5.81
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