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A three-nucleotide helix I is sufficient for full activity of a hammerhead ribozyme: advantages of an asymmetric design.

Trans-cleaving hammerhead ribozymes with long target-specific antisense sequences flanking the catalytic domain share some features with conventional antisense RNA and are therefore termed 'catalytic antisense RNAs'. Sequences 5' to the catalytic domain form helix I and sequences 3�...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Tabler, M, Homann, M, Tzortzakaki, S, Sczakiel, G
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1994
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308396/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.19.3958
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