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Radiation damage in single-particle cryo-electron microscopy: effects of dose and dose rate

Radiation damage is an important resolution limiting factor both in macromolecular X-ray crystallography and cryo-electron microscopy. Systematic studies in macromolecular X-ray crystallography greatly benefited from the use of dose, expressed as energy deposited per mass unit, which is derived from...

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Detalhes bibliográficos
Main Authors: Karuppasamy, Manikandan, Karimi Nejadasl, Fatemeh, Vulovic, Milos, Koster, Abraham J., Ravelli, Raimond B. G.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083915/
https://ncbi.nlm.nih.gov/pubmed/21525648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S090904951100820X
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