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Disease-toxicant screen reveals a neuroprotective interaction between Huntington’s disease and manganese exposure

Recognizing the similarities between Huntington’s disease pathophysiology and the neurotoxicology of various metals, we hypothesized that they may exhibit disease-toxicant interactions revealing cellular pathways underlying neurodegeneration. Here we utilize metals and the STHdh mouse striatal cell...

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Detalhes bibliográficos
Main Authors: Williams, B. Blairanne, Li, Daphne, Wegrzynowicz, Michal, Vadodaria, Bhavin K., Anderson, Joel G., Kwakye, Gunnar F., Aschner, Michael, Erikson, Keith M., Bowman, Aaron B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083829/
https://ncbi.nlm.nih.gov/pubmed/19845833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06445.x
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