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Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans

Pelvic organ prolapse (POP) is a common condition affecting almost half of women over the age of 50. The molecular and cellular mechanisms underlying this condition, however, remain poorly understood. Here we have reported that fibulin-5, an integrin-binding matricellular protein that is essential f...

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Detalhes bibliográficos
Main Authors: Budatha, Madhusudhan, Roshanravan, Shayzreen, Zheng, Qian, Weislander, Cecilia, Chapman, Shelby L., Davis, Elaine C., Starcher, Barry, Word, R. Ann, Yanagisawa, Hiromi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083772/
https://ncbi.nlm.nih.gov/pubmed/21519142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45636
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