Biodegradable Tri-Block Copolymer Poly(lactic acid)-poly(ethylene glycol)-poly(l-lysine)(PLA-PEG-PLL) as a Non-Viral Vector to Enhance Gene Transfection

Low cytotoxicity and high gene transfection efficiency are critical issues in designing current non-viral gene delivery vectors. The purpose of the present work was to synthesize the novel biodegradable poly (lactic acid)-poly(ethylene glycol)-poly(l-lysine) (PLA-PEG-PLL) copolymer, and explore its...

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Main Authors: Fu, Chunhua, Sun, Xiaoli, Liu, Donghua, Chen, Zhijing, Lu, Zaijun, Zhang, Na
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083711/
https://ncbi.nlm.nih.gov/pubmed/21541064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms12021371
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