Neutralizing IL-17 Prevents Obliterative Bronchiolitis in Murine Orthotopic Lung Transplantation

Obliterative bronchiolitis (OB) is the key impediment to the long term survival of lung transplant recipients and the lack of a robust pre-clinical model precludes examining OB immunopathogenesis. In the current study, lungs from C57BL/10 H-2(b) mice that are MHC compatible, but minor histocompatabi...

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Main Authors: Fan, Lin, Benson, Heather L., Vittal, Ragini, Mickler, Elizabeth A., Presson, Robin, Jo Fisher, Amanda, Cummings, Oscar W., Heidler, Kathleen M., Keller, Melissa R., Burlingham, William J., Wilkes, David S.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083638/
https://ncbi.nlm.nih.gov/pubmed/21521466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03482.x
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