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Three novel mutations in the ACTA2 gene in German patients with thoracic aortic aneurysms and dissections

Mutations in the gene encoding smooth muscle cell alpha actin (ACTA2) have recently been shown to cause familial thoracic aortic aneurysms leading to type A dissections (TAAD) and predispose to premature stroke and coronary artery disease. In order to further explore the role of ACTA2 variations in...

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Détails bibliographiques
Auteurs principaux: Hoffjan, Sabine, Waldmüller, Stephan, Blankenfeldt, Wulf, Kötting, Judith, Gehle, Petra, Binner, Priska, Epplen, Joerg T, Scheffold, Thomas
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083620/
https://ncbi.nlm.nih.gov/pubmed/21248741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.239
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