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A short purine oligonucleotide forms a highly stable triple helix with the promoter of the murine c-pim-1 proto-oncogene.

A homopurine-homopyrimidine region of murine c-pim-1 proto-oncogene was chosen as a target for triple-helix-forming oligonucleotide. Oligonucleotide 5'-GGG-GAGGGGGAGG-3' was shown to bind to its target sequence in the presence of 50 mM Na+ or K+, 10 mM MgCl2 and 20 mM Tris-acetate, pH 7.5....

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Bibliografski detalji
Glavni autori: Svinarchuk, F, Bertrand, J R, Malvy, C
Format: Artigo
Jezik:Inglês
Izdano: 1994
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC308356/
https://ncbi.nlm.nih.gov/pubmed/7937086
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