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The high stability of the triple helices formed between short purine oligonucleotides and SIV/HIV-2 vpx genes is determined by the targeted DNA structure.

In our previous works we have shown that the oligonucleotides 5'-GGGGAGGGGGAGG-3' and 5'-GGAGGGGGAGGGG-3' give very stable and specific triplexes with their target double stranded DNAs [Svinarchuk, F., Bertrand, J.-R. and Malvy, C. (1994) Nucleic Acids Res., 22, 3742-3747; Svinar...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Svinarchuk, F, Monnot, M, Merle, A, Malvy, C, Fermandjian, S
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1995
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.19.3831
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