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Aerobic Pd-Catalyzed sp(3) C–H Olefination: A Route to Both N-Heterocyclic Scaffolds and Alkenes

This communication describes a new method for the Pd/polyoxometalate-catalyzed aerobic olefination of unactivated sp(3) C–H bonds. Nitrogen heterocycles serve as directing groups, and air is used as the terminal oxidant. The products undergo reversible intramolecular Michael addition, which protects...

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Detalhes bibliográficos
Main Authors: Stowers, Kara J., Fortner, Kevin C., Sanford, Melanie S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083468/
https://ncbi.nlm.nih.gov/pubmed/21476513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2015586
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