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Interspecies Somatic Cell Nuclear Transfer Is Dependent on Compatible Mitochondrial DNA and Reprogramming Factors

Interspecies somatic cell nuclear transfer (iSCNT) involves the transfer of a nucleus or cell from one species into the cytoplasm of an enucleated oocyte from another. Once activated, reconstructed oocytes can be cultured in vitro to blastocyst, the final stage of preimplantation development. Howeve...

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Autores principales: Jiang, Yan, Kelly, Richard, Peters, Amy, Fulka, Helena, Dickinson, Adam, Mitchell, Daniel A., St. John, Justin C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083390/
https://ncbi.nlm.nih.gov/pubmed/21556135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014805
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