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Interspecies Somatic Cell Nuclear Transfer Is Dependent on Compatible Mitochondrial DNA and Reprogramming Factors

Interspecies somatic cell nuclear transfer (iSCNT) involves the transfer of a nucleus or cell from one species into the cytoplasm of an enucleated oocyte from another. Once activated, reconstructed oocytes can be cultured in vitro to blastocyst, the final stage of preimplantation development. Howeve...

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Bibliographic Details
Main Authors: Jiang, Yan, Kelly, Richard, Peters, Amy, Fulka, Helena, Dickinson, Adam, Mitchell, Daniel A., St. John, Justin C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083390/
https://ncbi.nlm.nih.gov/pubmed/21556135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014805
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