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Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

Survivin (BIRC5), a member of the inhibitor of apoptosis protein (IAP) family that inhibits caspases and blocks cell death is highly expressed in cancer and is associated with a poorer clinical outcome. Functioning simultaneously during cell division and apoptosis inhibition, survivin plays a pivota...

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Detalhes bibliográficos
Main Authors: Kelly, Ronan J, Lopez-Chavez, Ariel, Citrin, Deborah, Janik, John E, Morris, John C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083377/
https://ncbi.nlm.nih.gov/pubmed/21470426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-35
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