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The Essential Ubc4/Ubc5 Function in Yeast Is HECT E3-dependent, and RING E3-dependent Pathways Require Only Monoubiquitin Transfer by Ubc4
The ubiquitin (Ub)-conjugating enzymes Ubc4 and Ubc5 are involved in a variety of ubiquitination pathways in yeast, including Rsp5- and anaphase-promoting complex (APC)-mediated pathways. We have found the double deletion of UBC4 and UBC5 genes in yeast to be lethal. To investigate the essential pat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083232/ https://ncbi.nlm.nih.gov/pubmed/21357418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203968 |
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