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Selective Activation of the Transcription Factor NFAT1 by Calcium Microdomains near Ca(2+) Release-activated Ca(2+) (CRAC) Channels

NFATs are a family of Ca(2+)-dependent transcription factors that play a central role in the morphogenesis, development, and physiological activities of numerous distinct cell types and organ systems. Here, we visualize NFAT1 movement in and out of the nucleus in response to transient activation of...

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Bibliographic Details
Main Authors: Kar, Pulak, Nelson, Charmaine, Parekh, Anant B.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083208/
https://ncbi.nlm.nih.gov/pubmed/21325277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.220582
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