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Feedback Regulation of Endothelial Cell Surface Plasmin Generation by PKC-dependent Phosphorylation of Annexin A2

In response to blood vessel injury, hemostasis is initiated by platelet activation, advanced by thrombin generation, and tempered by fibrinolysis. The primary fibrinolytic protease, plasmin, can be activated either on a fibrin-containing thrombus or on cells. Annexin A2 (A2) heterotetramer (A2·p11)(...

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Bibliographische Detailangaben
Hauptverfasser: He, Kai-Li, Sui, Guangzhi, Xiong, Huabao, Broekman, M. Johan, Huang, Bihui, Marcus, Aaron J., Hajjar, Katherine A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083205/
https://ncbi.nlm.nih.gov/pubmed/21115493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185058
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