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N-terminal Half of the cGMP Phosphodiesterase γ-Subunit Contributes to Stabilization of the GTPase-accelerating Protein Complex

In the visual signal terminating transition state, the cyclic GMP phosphodiesterase (PDE6) inhibitory γ-subunit (PDEγ) stimulates GTPase activity of the α-subunit of transducin (αt) by enhancing the interaction between αt and its regulator of G protein signaling (RGS9), which is constitutively bound...

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Detalles Bibliográficos
Main Authors: Guo, Lian-Wang, Ruoho, Arnold E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083170/
https://ncbi.nlm.nih.gov/pubmed/21393250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210567
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