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Substrate Encapsulation: An Efficient Strategy for the RCM-Synthesis of Unsaturated ε-Lactones

[Image: see text] A facile substrate-encapsulated RCM-based synthesis of 7-membered lactones is reported. Coordination of the α,ω–dienyl ester precursor to the bulky Lewis acid (LA) aluminum tris(2,6-diphenylphenoxide) (ATPH) provides a protective extended steric pocket to the olefin moieties, there...

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Autori principali: Pentzer, Emily B., Gadzikwa, Tendai, Nguyen, SonBinh T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083066/
https://ncbi.nlm.nih.gov/pubmed/19053741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8022227
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