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Expression of CD44 3′-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis
The non-coding 3′-untranslated region (UTR) plays an important role in the regulation of microRNA (miRNA) functions, since it can bind and inactivate multiple miRNAs. Here, we show the 3′-UTR of CD44 is able to antagonize cytoplasmic miRNAs, and result in the increased translation of CD44 and downst...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082902/ https://ncbi.nlm.nih.gov/pubmed/21149267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1003 |
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