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Protein-Ligand interaction studies on 2, 4, 6- trisubstituted triazine derivatives as anti-malarial DHFR agents using AutoDock

The dihydrofolate reductase (DHFR) domain of P. falciparum is one of the few well defined targets in malarial chemotherapy. The enzyme catalyzes the nicotinamide adenine dinucleotide phosphate (NADPH) dependent reduction of dihydrofolate to tetrahydrofolate. Protein-ligand interactions were studied...

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Sonraí Bibleagrafaíochta
Main Authors: Adinarayana, Katika Prabhakara Surya, Devi, Rednam Karuna
Formáid: Artigo
Teanga:Inglês
Foilsithe: Biomedical Informatics 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082864/
https://ncbi.nlm.nih.gov/pubmed/21544169
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