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Attenuated Listeria monocytogenes vaccine vectors expressing Influenza A nucleoprotein: preclinical evaluation and oral inoculation of volunteers
Listeria monocytogenes vectors have shown promise for delivery of viral and tumor antigens in animals. We used 2 mutant vector strains deleted for actA/plcB (BMB72) and actA/inlB (BMB54) and engineered both strains to secrete a heterologous nucleoprotein antigen from the Influenza A virus. Strains w...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082616/ https://ncbi.nlm.nih.gov/pubmed/21338384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1348-0421.2011.00322.x |
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