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Safety and Shedding of an Attenuated Strain of Listeria monocytogenes with a Deletion of actA/plcB in Adult Volunteers: a Dose Escalation Study of Oral Inoculation

Listeria monocytogenes is an intracellular bacterial pathogen which causes bacteremia and has a tropism for the central nervous system and a propensity to cause maternofetal infection. L. monocytogenes has been shown to be an effective prophylactic and a therapeutic vaccine vector for viral and tumo...

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Detalhes bibliográficos
Main Authors: Angelakopoulos, Haroula, Loock, Katharina, Sisul, David M., Jensen, Eric R., Miller, Jeff F., Hohmann, Elizabeth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128066/
https://ncbi.nlm.nih.gov/pubmed/12065500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3592-3601.2002
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