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T Cell Chemo-Vaccination Effects after Repeated Mucosal SHIV Exposures and Oral Pre-Exposure Prophylaxis

Pre-exposure prophylaxis (PrEP) with anti-viral drugs is currently in clinical trials for the prevention of HIV infection. Induction of adaptive immune responses to virus exposures during anti-viral drug administration, i.e., a “chemo-vaccination” effect, could contribute to PrEP efficacy. To study...

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Detalhes bibliográficos
Main Authors: Kersh, Ellen N., Adams, Debra R., Youngpairoj, Ae S., Luo, Wei, Zheng, Qi, Cong, Mian-er, Aung, Wutyi, Mitchell, James, Otten, Ron, Hendry, R. Michael, Heneine, Walid, McNicholl, Janet, Garcia-Lerma, J. Gerardo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082568/
https://ncbi.nlm.nih.gov/pubmed/21541293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019295
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