Neurosteroid Dehydroepiandrosterone Interacts with Nerve Growth Factor (NGF) Receptors, Preventing Neuronal Apoptosis

The neurosteroid dehydroepiandrosterone (DHEA), produced by neurons and glia, affects multiple processes in the brain, including neuronal survival and neurogenesis during development and in aging. We provide evidence that DHEA interacts with pro-survival TrkA and pro-death p75(NTR) membrane receptor...

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Detaylı Bibliyografya
Asıl Yazarlar: Lazaridis, Iakovos, Charalampopoulos, Ioannis, Alexaki, Vassilia-Ismini, Avlonitis, Nicolaos, Pediaditakis, Iosif, Efstathopoulos, Paschalis, Calogeropoulou, Theodora, Castanas, Elias, Gravanis, Achille
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082517/
https://ncbi.nlm.nih.gov/pubmed/21541365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001051
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