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An Electrochemical Supersandwich Assay for Sensitive and Selective DNA Detection in Complex Matrices
In a traditional sandwich assay, a DNA target hybridizes to a single copy of the signal probe. Here we employ a modified signal probe containing a methylene blue (a redox moiety) label and a “sticky end.” When a DNA target hybridizes this signal probe, the sticky end remains free to hybridize anothe...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082473/ https://ncbi.nlm.nih.gov/pubmed/20873767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104998m |
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