An Electrochemical Supersandwich Assay for Sensitive and Selective DNA Detection in Complex Matrices

In a traditional sandwich assay, a DNA target hybridizes to a single copy of the signal probe. Here we employ a modified signal probe containing a methylene blue (a redox moiety) label and a “sticky end.” When a DNA target hybridizes this signal probe, the sticky end remains free to hybridize anothe...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Xia, Fan, White, Ryan J., Zuo, Xiaolei, Patterson, Adriana, Xiao, Yi, Kang, Di, Gong, Xiong, Plaxco, Kevin W., Heeger, Alan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082473/
https://ncbi.nlm.nih.gov/pubmed/20873767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104998m
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky