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JunD and JunB Integrate Prostaglandin E(2) Activation of Breast Cancer-Associated Proximal Aromatase Promoters
Aromatase is the key enzyme in estrogen biosynthesis. Normal breast adipose tissue expresses low levels of aromatase via the distal promoter I.4. Breast adipose tissue surrounding a tumor exhibits excessive aromatase expression controlled by proximal aromatase promoters I.3/II, leading to high local...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082330/ https://ncbi.nlm.nih.gov/pubmed/21393445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0368 |
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