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JunD and JunB Integrate Prostaglandin E(2) Activation of Breast Cancer-Associated Proximal Aromatase Promoters

Aromatase is the key enzyme in estrogen biosynthesis. Normal breast adipose tissue expresses low levels of aromatase via the distal promoter I.4. Breast adipose tissue surrounding a tumor exhibits excessive aromatase expression controlled by proximal aromatase promoters I.3/II, leading to high local...

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Bibliographic Details
Main Authors: Chen, Dong, Reierstad, Scott, Fang, Feng, Bulun, Serdar E.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082330/
https://ncbi.nlm.nih.gov/pubmed/21393445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0368
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