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The Stimulation of HSD17B7 Expression by Estradiol Provides a Powerful Feed-Forward Mechanism for Estradiol Biosynthesis in Breast Cancer Cells
Our laboratory has previously cloned and purified an ovarian protein found to be a novel 17β-hydroxysteroid dehydrogenase type 7 enzyme (HSD17B7) (formerly prolactin receptor-associated protein) that converts the weak estrogen, estrone, to the highly potent estradiol. The regulation of this enzyme h...
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Główni autorzy: | , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Endocrine Society
2011
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082328/ https://ncbi.nlm.nih.gov/pubmed/21372145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0261 |
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