The Stimulation of HSD17B7 Expression by Estradiol Provides a Powerful Feed-Forward Mechanism for Estradiol Biosynthesis in Breast Cancer Cells

Our laboratory has previously cloned and purified an ovarian protein found to be a novel 17β-hydroxysteroid dehydrogenase type 7 enzyme (HSD17B7) (formerly prolactin receptor-associated protein) that converts the weak estrogen, estrone, to the highly potent estradiol. The regulation of this enzyme h...

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Main Authors: Shehu, Aurora, Albarracin, Constance, Devi, Y. Sangeeta, Luther, Kristin, Halperin, Julia, Le, Jamie, Mao, Jifang, Duan, Rachel W., Frasor, Jonna, Gibori, Geula
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082328/
https://ncbi.nlm.nih.gov/pubmed/21372145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0261
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