Concerted Action of Aldehyde Dehydrogenases Influences Depot-Specific Fat Formation

Vitamin A metabolite retinoic acid (RA) regulates life-sustaining differentiation processes and metabolic homeostasis. The aldehyde dehydrogenase-1 (Aldh1) family of enzymes (Aldh1a1, a2, and a3) catalyzes RA production from retinaldehyde and thereby controls concentrations of this transcriptionally...

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Autors principals: Reichert, Barbara, Yasmeen, Rumana, Jeyakumar, Shanmugam M., Yang, Fangping, Thomou, Thomas, Alder, Hansjuerg, Duester, Gregg, Maiseyeu, Andrei, Mihai, Georgeta, Harrison, Earl H., Rajagopalan, Sanjay, Kirkland, James L., Ziouzenkova, Ouliana
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2011
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082326/
https://ncbi.nlm.nih.gov/pubmed/21436255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0465
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